TEADs are regulated by S-palmitoylation of a conserved cysteine located in the region of the protein that regulates transcription factors . The Royal Society of Chemists published the findings in The RSC Med. Chem., published in February 2023, and published online at 10.1039/D3MD00264K .
Chloroacetamide Fragment Library Screening Identifies New Scaffolds for Covalent Inhibition of the TEAD•YAP1 Interaction
