AI Summary
The use of sNfL Z score in children and adolescents allows for more accurate estimation of neuroaxonal damage in individual patients than absolute sNfL values. Summary unavailable.
The established normative sNfL values in children and adolescents provide a foundation for the clinical application of sNfL in the paediatric population. Compared with absolute sNfL values, the use of sNfL Z score was associated with higher effect size metrics and allowed for more accurate estimation of the extent of ongoing neuroaxonal damage in individual patients.