Discovery and computational studies of piperidine/piperazine-based compounds endowed with sigma receptor affinity

This article is licensed under a Laura De Luca, Lisa Lombardo, Salvatore Mirabile, Agostino Marrazzo, Maria Dichiara, Giuseppe Cosentino, Emanuele Amata, Rosaria Gitto
Herein we describe our efforts to identify sigma receptor 1 (S1R) ligands through a screening campaign on our in-house collection of piperidine/piperazine-based compounds . Our investigations led to the discovery of…

Leave a Reply