RSC Medicine Accepted Manuscript, Chem., 2023
DOI: 10.1039/D2MD00289B, Research ArticleChloe Goldsmith, Peter Cossar, Jennette Sakoff, Christopher Scarlett, Adam McCluskey, Jufeng Sun, Jennifer R Baker, Cecilia Russell, Hong Ngoc Thuy Pham
Four focused libraries were created and synthesised from lead 1, ( N-( 4 )(( 4 – ( 3: methoxyphenyl ) sulfonyll ) piperazin ( Suprazol ) 1, 2( diazol ), acetamide, a S100A2 / p53 protein-protein interaction inhibitor based on an in silico modelling driven hypothesis. A screening for growth inhibition was done against …
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