Visible and NIR light photoactivatable o-hydroxycinnamate system for efficient drug release with fluorescence monitoring

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RSC Med. Chem., 2023, 14,1088-1100
DOI: 10.1039/D2MD00438K, Research ArticleAjay Gupta, Neelu Singh, Aryan Gautam, Neetesh Dhakar, Sunil Kumar, Pijus K. Sasmal
We report a photoactivatable o-hydroxycinnamate–gemcitabine prodrug that shows an efficient drug release with real-time monitoring, and dose- and temporally-controlled photocytotoxicity upon visible (one-photon) or NIR (two-photon) light irradiation.
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